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The abnormal calcium signaling seen in AD further accelerates neuronal dysfunction and synaptic loss, particularly in brain regions critical for memory and learning ( Collectively, these biochemical and molecular disruptions lead to significant impairments in brain function

PMID: 166 CollinsLCGattaLADotters-KatzSKKullerJASchustDJ

Moreover, the biomarkers useful in detecting pre-clinical dementia are measured via ERP and quantitative EEG (qEEG) testing, which require sophisticated data processing and comparisons with normative database references values

However, the study lacked essential methodological details, including dosage and treatment duration, limiting the reproducibility and interpretability of the findings (Kaushik et al., 2018)

doi: 10.1016/j.chemosphere.2010.09.071 53 NadalMDomingoJL