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Strength loss typically accompanies muscle loss, making stable or improving numbers a positive indicator

The difference is substantial and clinically meaningful

For example, low IGF-1 will have different effects on children compared to adults

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These codes add clinical detail that M25.512 alone doesn't convey: G89.11: Acute pain due to trauma G89.29: Other chronic pain G89.4: Chronic pain syndrome Here's the rule from ICD-10-CM guidelines: don't assign G89 codes unless pain is specifically documented as acute, chronic, post-procedural, or neoplasm-related