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Unlike rd10 , which carries a missense mutation in exon 13 of phosphodiesterase 6B ( Pde6b ) 29 , the Rho P23H model carries the p.Pro23His mutation in the rhodopsin gene and shows progressive retinal degeneration similar to that seen in patients with autosomal dominant retinitis pigmentosa 32

The 10 mg vial is freeze-dried for stability and can be reconstituted with bacteriostatic water to produce a clear solution for in vitro or preclinical use

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It houses 7080% of the immune system, synthesizes essential neurotransmitters like serotonin, and regulates inflammation throughout the body

For subcutaneous injection protocols, standard bacteriostatic water reconstitution applies