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However, more research should focus on the long-term effects of NR or other NAD + precursors in neurodegenerative patients

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Potential pancreatitis risk : As with other GLP-1-based therapies, there is a theoretical concern regarding pancreatitis, though causality has not been firmly established in trials to date

Risk increases significantly after 2+ years of use Post-bariatric surgery patients gastric bypass removes or bypasses the sites of intrinsic factor production and B12 absorption People with autoimmune conditions pernicious anemia (anti-intrinsic factor antibodies) and autoimmune gastritis directly block absorption People with GI conditions Crohns disease (especially ileal involvement), celiac disease, SIBO, and chronic H

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