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57 (3), B109B114

The molecular weight of IGF-1 LR3 is approximately 9.2 kilodaltons, which is slightly higher than natural IGF-1 due to the addition of 13 amino acids at the N-terminus and the substitution of arginine for glutamic acid at position 3

Thus, it needs HCl to dissolve and release it from its fiber carrier

The results of these two tissues are provided in Additional files 5, 6, 7, 8, 9, and 10 for tissue response comparison

Furthermore, while these agents are relatively selective at standard doses, coadministration with serotonergic drugs like selective serotonin reuptake inhibitors requires caution due to the risk of precipitating serotonin syndrome , characterized by autonomic instability, altered mental status, and neuromuscular hyperactivity