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Ninichuk, V

The universal facilitator of GSH breakdown and only know glutathionase enzyme is -glutamyltranspeptidase (GGT) which is located on the outer leaf of the cell's plasma membrane

lights on from 7 am, lights off from 7 pm), with free access to standard laboratory chow and tap water

10 Proof-of-concept treatments were validated in Pfa1 cells, which were knocked out of endogenous GPX4 and transfected to overexpress murine mScarlet-tagged GPX4 WT (red) or GPX4 R152H (blue)