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Future studies combining -cell states defined by scRNA-seq and snATAC-seq with quantitative measures of SCFA, indole derivatives, or endotoxemia have the potential to reveal whether specific -cell subpopulations preferentially associate with distinct microbiota-derived signatures or display differential transcriptional responses to incretin- and SCFA-dependent interventions, thereby advancing a systems-level understanding of microbiota-cell interactions

C.VenetisC.et al (2020)

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2020 349.Dutra HL, Dos Santos LM, Caragata EP, Silva JB, Villela DA, Maciel-de-Freitas R, et al