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A liver biopsy is essential for the diagnosis of chronic hepatitis

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Sample size As the primary outcome is the reduction in the extent and severity of disease determined as change in PASI score from baseline (T0) to T1 in PS patients supplemented with prebiotic ITFs compared with PS patients supplemented with placebo over the 8-week intervention, we assumed a 50% reduction in PASI (PASI50) as being a clinically meaningful improvement in PS treatment [34]

Hatamie, A., Marahel, F., Sharifat, A., Talanta , 2018, vol

The efficacy of L-Glutamine is highly dose-dependent, and the optimal dosage varies significantly based on the severity of the intestinal permeability and the specific goals of the patient