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J Mol Evol (2003) 56:397406

Somko J, Estvez-Lpez F, Kujawski S, Zawadka-Kunikowska M, Tafil-Klawe M, Klawe JJ, et al

Conversely, the de novo pathway and Preiss Handler pathway synthesize NAD + using nicotinic acid (NA) and tryptophan as substrates, respectively, albeit in smaller quantities