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According to pharmacopoeial standards, sterile water for injection is also used as a solvent for sterile powder formulations or as a diluent for injectable products

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Upon intradermal administration of the AdGMCAIX-transduced autologous DCs back into the patient, the DCs are expected to activate a cytotoxic T lymphocytemediated response against tumor cells positive for the CA9 antigen, and generate memory T cells, potentially resulting in decreased tumor growth

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The loss of proteoglycans is a major biochemical change observed in IDD

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Most evidence comes from in vitro studies or small human trials, not large-scale randomized controlled trials

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