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The FDA approved generic versions of Vyvanse from 11 drugmakers, including U.S.-based drugmakers Mallinckrodt and Viatris, UK-based Hikma Pharmaceuticals, and Indian drugmaker Sun Pharmaceutical Industries, last year after Takeda lost exclusivity over the drug

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The theoretical cancer risk from telomerase activation is the main long-term concern

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Liver toxicity ranges from asymptomatic mild elevation of transaminases with spontaneous resolution to liver failure and death.Current best practice involves maintaining a high level of clinical suspicion and conducting thorough hepatological investigations, guided by the international RUCAM criteria, a diagnostic algorithm for DILI