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At first glance, the difference seems minor

doi: 10.1016/j.bcp.2021.114769 60 CeremugaMStelaMJanikEGorniakLSynowiecESliwinskiTet al

Research demonstrates TB-500 reduces inflammatory markers including IL-6 and TNF-alpha while releasing the anti-inflammatory fragment acetyl-SDKP, creating conditions that favor repair over chronic inflammation