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This reaction also generates NADH 13

Since the discovery of FSP1, more and more GPX4-independent ferroptosis pathways have been discovered in various physiological and pathological processes Drugs targeting GPX4-independent ferroptosis pathway may become a new direction for the treatment of diseases

270 LiJ.LiW.SuJ.LiuW.AlturaB

L.GaedigkA.HachadH.JiY.et al (2021)

306 These results indicate that p53 expressed in macrophages plays a critical role in the inhibition of atherosclerosis progression and identify a novel target for regulating plaque stability