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Description

AHKCu stands for alaninehistidinelysine copper, i.e., a tripeptide of alanine, histidine, and lysine bound to a copper ion

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These newborns are at risk for life threatening salt wasting crises during the first weeks of life and need urgent hormonal and genetic assessment (at least karyotype analysis), followed by further genetic analyses to define the specific steroidogenesis defect and its treatment [73]

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These events were reported early during therapy, and tended to be transient and/or responsive to dosage reduction

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PepPal (2026) 6

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