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Mice were administered R001 (5 mg/kg, oral gavage, 100 L PBS with 5% DMSO) every day, 5 times per week for 75 days

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Pericytes contribute to regulating BBB permeability and cerebral blood flow, and they also participate in the biological clearance of harmful foreign compounds[24, 25]

Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, et al