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The main organ involved in primary creatine deficiency is the brain, and 1H-MRS may show a significant reduction or absence of the creatine peak

"Randomized clinical trial of how long-term glutathione supplementation offers protection from oxidative damage and improves HbA1c in elderly type 2 diabetic patients." Antioxidants

It may also support visual clarity and reduce age-related oxidative changes in the eyes

High concentrations of melatonin are pro-oxidant in cancer cells, but do not increase ROS production in lymphocytes (Radogna et al., 2009)

While we cant avoid all environmental toxins, you can take steps like using air filters indoors, avoiding known sources of pollutants