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Abscence of detectable Philadelphia chromosome (Ph+) and Bcr/Abl positive cells in lin- SP bone marrow progenitor cells from patients with CML

In summary, copper metabolism is a complex process that involves multiple mechanisms to regulate copper absorption, transport, storage, and elimination

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The obtained results suggested that the self-renewal potential of both OCSCs and BCSCs gradually increased till S3 and S2 generation respectively with logarithmic deterioration of the self-renewal ability, however, no further spheroid formation was detected in S6 and S7 generations, respectively (Figure 3 a)