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However, in cases of chronic, severe deficiency, it can lead to pancytopenia, hemolytic anemia, and serious neurological (such as coordination disorders and paresthesias) or psychiatric conditions, including depression, mania, or memory impairment

For metabolomic and molecular studies, at the end of treatment (at 8 wk of age), the brains were surgically removed after cervical dislocation and stored at 80C

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If you think it would help, you might try an over-the-counter topical in the meantime before your appointment