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Hesperidin (Matias et al., 2017), rutin (El-Sayed el et al., 2008), and rhamno (Omar et al., 2017) can reduce the amount of free Ca 2+ located between brain cells when fighting against neurogenic excitotoxicity and can attenuate the decrease of the mitochondrial membrane potential and increase caspase-3 activity (Lutz et al., 2015)

ROS can also influence tumor energy metabolism by regulating critical metabolic enzymes, skewing the tumor toward the pentose phosphate pathway to maintain its reducibility

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10.3390/md13021037 263 SuY

7A) and significantly reduced the wound width in scratch assays under LPS challenge (Fig