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The ultimate goal of the research is to develop mitochondrial-targeted therapies that can intelligently respond to pathological states and to achieve stage-based individualized diagnosis and treatment of sepsis using mitochondrial function markers, thereby systematically innovating the existing clinical prevention and treatment strategies

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The Gateway destination vector pAG415GAL-ccdB (CEN/ARS-based, GAL1 promoter, and LEU2 marker) was purchased from Addgene and served as the yeast expression vector