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Yang and Tsai, 2022

Estruturalmente deriva do esqueleto base do GHRP-1, tendo sido, no entanto, modificado de forma deliberada para apresentar um perfil farmacolgico particularmente estreito

Pyroptosis plays a role in containing infections and promoting immune clearance, but excessive or dysregulated pyroptosis has also been implicated in the pathogenesis of sterile inflammatory and autoimmune diseases

However, histological changes are not pathognomonic for NTM infection

These include molecules and enzymatic regulators involved in the metabolism of glucose, arginine, tryptophan, glutamine, cysteine, lipids, ROS, and AMP-activated protein kinase (AMPK) (28) ( Figure 2 )