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Dysfunction of ABCG2 plays a significant role in pediatric-onset hyperuricemia and gout [22]

The insulin-like growth factor system in chronic kidney disease: Pathophysiology and therapeutic opportunities

Furthermore, studies undertaken in vitro using isolated mouse hepatocytes have revealed that AMAP has a markedly reduced propensity to cause cytotoxicity when compared with acetaminophen, even though AMAP treatment results in higher levels of covalent binding to proteins (Holme et al