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for the wave subgroup, I 2 = 11%, P = 0.32

Due to the degradation of such polymeric NPs, the encapsulated drug is released over a predetermined period

Typically, iron homeostasis is maintained by regulating iron absorption

NRF2, a transcription factor for stress response and beyond

The loss of BRCA1 and BRCA2 leads to the impairment of homologous recombination repair functions, rendering tumor cells unable to effectively repair DNA damage, consequently causing genomic instability and tumor progression ( When these cells experience DNA damage, they cannot repair it through the HRR pathway, leading to cell death (49)