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IV therapy ensures that glutathione is delivered directly into the bloodstream, bypassing the digestive system, where its effectiveness could be reduced

Brain slabs were dehydrated in graded ethanol and embedded in paraffin

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[108] These findings attest to the structural importance of specific residues outside metal coordination sites for SOD1 metal binding, which may not ligate metals themselves but can modulate protein conformation around coordinating residues to influence metal binding