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Omega-3 Polyunsaturated Fatty Acids (Omega-3 or n-3 PUFAs) , eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA), are broad-spectrum anti-inflammatory compounds that modulate several pathways of inflammation including leukocyte chemotaxis, adhesion molecule expression, and leukocyte-endothelial adhesive interactions, inflammatory cytokine synthesis and T cell reactivity 708

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Asp can also act as an amino acid exchange factor, becoming a medium for amino acids in and out of cells, especially histidine, arginine and serine

However, some metabolic processes result in toxicity due to renal excretion (Savage, 1970

When the microbiota starts to produce toxic metabolites that interfere with the gut-liver axis and cause metabolic dysfunction, dysbiosis is confirmed, and eventually, chronic disease development occurs