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As a water-soluble vitamin, excess B12 is typically excreted in urine rather than stored

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Neuropsychiatric conditions are common in patients with B12 deficiency, although the available studies are heterogeneous regarding patient characteristics and the diagnostic tools employed [3,4,5,29,33,82,83,84,85,86,87]

[19] The gut is compromised in celiac disease, and this can cause reduced nutrient absorption, including iron absorption

The B12 component in LIPO-C is secondary to the lipotropic agents, so concurrent oral supplementation is safe and often beneficial for patients with documented B12 deficiency