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and Brown, B.I

Dysfunctional cell and tissue metabolism, in particular, has been identified as a key factor expanding the hallmark of both immune decline and ageing (Lpez-Otn et al, 2023)

Regarding stability and biocompatibility, novel smart coatings or hybrid structures can be developed: for example, designing pH- or enzyme-responsive polymer shells that remain stable in circulation but degrade at the tumor site to expose targeting ligands, enabling precise delivery

Cigarette smoke activates cftr through ros-stimulated camp signaling in human bronchial epithelial cells

Previous studies also showed that some patients showing no evident cerebellar atrophy respond well to immunotherapies and that the clinical improvement correlates well with a fall in Ab titers [3, 6]