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In this case, the mutation is likely to result in higher expression of the neighboring genes and enhanced BDO degradation via oxidation by the encoded dehydrogenases

Furthermore, mortality was found to be increased in a European population of relatively low selenium status (plasma selenium 89 g/l) on long-term supplementation with 300 g/d (as selenium-yeast) ( Reference Rayman, Winther and Pastor-Barriuso 111 )

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