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Knocking down ACSL4 also remarkably reduces the levels of 5-hydroxyeicosatetraenoic acid (5-HETE) thereby reducing arsenic-induced MASH

No participants developed antibodies against AOD-9604, indicating it doesnt trigger immune responses

The cell pellet was resuspended in lysis buffer A 1 (25 mM HEPES, pH 7.5, 500 mM NaCl, 1 mM Tris (2-carboxyethyl) phosphine (TCEP)) supplemented with EDTA-free Protease Inhibitor Cocktail (Selleck)