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Active lesions maintain this pattern of partial regeneration until episode remission, when, finally, regeneration overcomes myelin destruction

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(1991) documented that IV infusion of 2 g/m^2 raised plasma glutathione from 17.5 umol/L to 823 umol/L -- a roughly 47-fold increase -- with a half-life of approximately 14 minutes (Aebi et al., 1991)