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In studies of limited quality in non-human mammalian cells in vitro, aspartame induced DNA strand breaks in MadinDarby canine kidney (MDCK) cells but did not induce unscheduled DNA synthesis in rat primary hepatocytes

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Martin V, Najbar W, Gueguen S, Grousson D, Eun HM, Lebreux B, Aubert A (2002): Treatment of canine parvoviral enteritis with interferon-omega in a placebo-controlled challenge trial