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The amyloid cascade hypothesis posits A to be the central driver of AD either by abnormal production or hindered clearance, resulting in aggregate stress and neuronal dysfunction/death in a sequential manner (Karran et al., 2011

& McPartland, J

Several factors explain this gap: Adherence drops

Anti-inflammatory diets like the autoimmune protocol (AIP), Mediterranean diet, or elimination-based approaches reduce dietary triggers of immune activation