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Excess salt exacerbates blood-brain barrier disruption via a p38/MAPK/SGK1-dependent pathway in permanent cerebral ischemia

10.1016/j.biopha.2016.10.011 98 TeraoJ

Autophagy dismantles worn or damaged components and delivers them to the lysosome, a small acidic compartment that digests waste

Chen C, Ai QD, Wei YH

It is a critical process that plays essential roles in organismal development, homeostasis maintenance, and disease pathogenesis ( Aberrent cell death is closely associated with various diseases, and its study holds significant implications for understanding the essence of life processes and for advancing disease treatment, especially in the context of tumors, neurodegenerative diseases, and inflammatory conditions ( Uveitis is a leading cause of vision-threatening ocular inflammation worldwide, characterized by a complex pathogenesis involving immune cell infiltration, oxidative stress, and various forms of cell death ( Table 1 )