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The systemic inflammatory response generated by the production of cytokines and chemokines during intestinal I/R injury might profoundly disrupt the bloodbrain barrier (BBB) (Guo et al., 2025)

But for others, there are many non-allergic symptoms

They also found that OA-GL17d treatment and miR-663a inhibition activated the Smad signaling pathway and significantly reversed the effect of miR-663a mimic on the Smad pathway, thereby promoting skin wound healing