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Any patient with neurological symptoms: intramuscular injection, regardless of baseline procedure

demonstrated that reducing Gln levels, inhibiting the transmembrane transport of Gln (using V-9302), or blocking Gln metabolism (with CB-839) markedly decreased mesothelioma cell proliferation, spheroid formation, invasion, and migration

These pathways converge influencing cell fate decisions (survival vs death), proliferation rates, migration patterns, and differentiation states

With a 20-day active period and 4 months off, the total annual protocol commitment is 60 active days spread across the year

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