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These effects were mostly linked to the positive regulation of PGC-1 [111], a coactivator of transcription needed for mitochondrial biogenesis [123]

Y.WangS.MiaoW.et al (2021)

In practical terms, this means TB-500 helps cells physically move toward injury sites a process critical for tissue regeneration

Sestrin2 overexpression inhibits proliferation and epithelial-mesenchymal transition and induces autophagy through the AMPK/mTOR signaling pathway in human prostate cancer cells