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Metal-based systems (MnO, Cu 2 , Fe 3 ) deplete GSH and generate ROS, with imaging potential, though metal toxicity and accumulation are concerns

10.1002/cam4.2004 104 JohnsonS

Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice

Cheng, Q

Multiple sclerosis: NAC reduces tumour necrosis factor toxicity, and in an animal model of multiple sclerosis, it prevents the development of multiple sclerosis-like pathology [24]