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Description

PLoS One 14, e0222613

doi: 10.18632/oncotarget.11923 88 VenkateshD.O'BrienN

Inflammatory cytokines IL-1 and IL-18 present in the ovarian tissue and FF in PCOS patients alter the follicular microenvironment by binding to receptors like IL-1R and TLR4 on the GCs, activating NF-B, which subsequently translocates into the nucleus (50)