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A study reported an unconventional phenotype of LPSmediated BACH1defective macrophages marked by both proinflammatory traits (enhanced inflammasome activation) as well as antiinflammatory (high expression levels of HO1 and M2 markers) attributes

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[DOI] [PubMed] [Google Scholar] 44.Saunthararajah Y

Although the exact mechanism behind this synergy remains unclear, it may involve destabilization of the bacterial outer membrane through the depolymerase action 135