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Cell 183 , 377394.e21 (2020)

however, data from elegant genetic studies in mice suggest that NF-B could equally be a difficult therapeutic target in inflammatory diseases. This pathway regulates proinflammatory pathways (including the generation of TNF-), inflammatory cell recruitment, but also has leukocyte apoptotic functions, which can help resolve inflammation

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Zhao, L., Yu, G., Han, Q., Cui, C

10.1038/ncomms10894 106 NoctorG.QuevalG.MhamdiA.ChaouchS.FoyerC