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Abstract Inflammatory bowel disease (IBD), which includes Crohns disease and ulcerative colitis, is a nonspecific chronic inflammation of the gastrointestinal tract

It was concluded that both sex hormones and opioids modulate the composition and activity of the gut microbiome and that the effects of chronic opioid exposure on sex hormone regulation could in turn influence microbiome in a sex-dependent manner

Verkerk AJ, Pieretti M, Sutcliffe JS, Fu Y-H, Kuhl DP, Pizzuti A, et al

Symptoms may also take a while to emerge

B-GOS did not, however, compromise the main olanzapine antipsychotic mechanism, which is mediated through blockage of serotonin 5-HT2A receptors