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It is important to note that in BRCA1-deficient mammary cells, activation of NRF2 via small interfering RNA inhibition of KEAP1 rescued the survival defect linked with loss of BRCA1 and caused ROS levels restoration, indicating that this mechanism is important (237, 240)

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[Abstract] Cell Biochem Funct

Filtered after second heating, the filtrate was made up to mark in a 25 mL flask and kept refrigerated pending total metal determination by AAS