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These antibodies can neutralize the peptides intended effect, but they can also, in some cases, cross-react with endogenous peptides the body produces naturally, leading to consequences that are difficult to predict and may take months to manifest

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Numerous papers have reported that stable gastric pentadecapeptide BPC 157 can regulate angiogenesis during the healing process by rescuing the duodenal lesions in rats through interacting with the nitric oxide (NO) system and reducing of free radical formation, 14 and also can resolve pringle maneuver 15 and hippocampal ischemic damage in rats due to ischemia or reperfusion

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