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This study for the first time provides a rigorous indication that such a link exists in humans as well

This is particularly important for essential and abundant proteins whose overoxidation would lead to loss of cell viability and requires new protein synthesis to replace inactivated proteins

early thrombolytic therapy or PCI significantly reduces mortality by restoring coronary blood flow, yet reperfusion of ischemic myocardium still triggers an inflammatory response that exacerbates myocardial necrosis and worsens cardiac dysfunction [71]

2015;308(2):G6375

In a Phase I clinical study, MM-302 demonstrated enhanced tumor-specific uptake and manageable safety in HER2-positive metastatic breast cancer patients [122]