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Academic research continues, but the approval pathway that would give these compounds legal drug status faces structural economic barriers that regulatory posture changes don't resolve

Therefore, we used the glycoengineered MKN45 ST6GalNAc-I (MST6-I) gastric cancer cell line, which overexpresses ST6GalNAc-I and synthesizes the aberrant STn O -glycan, and the MKN45 Mock control cell line, which is negative for STn [Figure 1A and B]

4-en-VPA and propionic acid metabolites resulting from -oxidation could also promote hyperammonaemia [19, 24]

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