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The structure-functional properties of these 5 specific viral-hijacked host cellular factors, their ultimate pathophysiological consequence(s) due to virus-induced HMRD in acute COVID-19 and during long-COVID, the persistent virus-free PASC disease state, is comprehensively described below

This approach elevates mechanistic toxicology from a downstream regulatory hurdle to an indispensable, a priori design tool

Additionally, antibody-based biomarkers hold promise for predicting treatment outcomes and identifying individuals at increased risk of disease relapse, thereby informing clinical decision-making, and improving patient outcomes

Emerging role of the cGAS-STING signaling pathway in autoimmune diseases: Biologic function, mechanisms and clinical prospection

[DOI] [PubMed] [Google Scholar] 182.Zhang D., Lu C., Whiteman M., Chance B., Armstrong J.S