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For a patient whose entire complaint can be summarized as I cannot sleep and therefore everything else suffers, addressing the sleep deficiency directly before layering in energy or anabolic therapies is the more precise clinical decision

B12 needs folate and the other B vitamins in order to function properly

We of course appreciate that GP Practices are under huge pressure at the moment and that many are experiencing staff shortages but there is always a way around these problems

Given the short half-life, twice-daily dosing provides additional exposure compared to once-daily protocols at the same total dose