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5c), indicated significant reductions in key genes of the NF-B and TNF signalling pathways in livers from mice overexpressing AGXT, including Nfkb2 , Relb and Tnf as well as chemokine (CC motif) ligand 2 ( Ccl2 ) and Ccl5 that are known as drivers and therapeutic targets in MASH together with Ccr2 that regulate the recruitment of monocyte-derived cells in MASH 48

Sierra, L., Roco, J., Alarcon, G., Medina, M., Van Nieuwenhove, C., de Bruno, M

In this study, 3236 individuals without pre-existing cardiovascular disease were examined, with measurements taken for 112 plasma metabolites (small molecules resulting from metabolism)

This fundamental difference makes it particularly appealing for long-term protocols