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Four fractions of 1 CV were eluted with 250 mM imidazole

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Figure 2 Flippases are members of the P4-type ATPase family with a similar structure containing 10 transmembrane domains, an actuator domain, a phosphorylation domain, and a nucleotide-binding domain associating with an accessory subunit Cdc50, forming a heterodimeric complex

injections of 100 nmol kg 1 MK-801 ( n = 7 mice and n = 4 cages), 100 nmol kg 1 GLP-1 ( n = 6 mice and n = 3 cages), 100 nmol kg 1 , GLP-1MK-801 ( n = 6 mice and n = 3 cages), co-administration of 100 nmol kg 1 GLP-1 and 100 nmol kg 1 MK-801 ( n = 6 mice and n = 3 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 14 days

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