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doi: 10.1080/1028415X.2023.2288387 9

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98 While TNF- stimulates monocytes/macrophages and maintains granuloma integrity, high levels may exacerbate pathology

It is also important to consider the activity of fasting and/or fasting-mimicking conditions on the metabolism and autophagy flux of immune cells, as both significantly influence the outcome of immune responses (60)